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      (Hypromellose Acetate Succinate)

      Shin-Etsu AQOAT® (hypromellose acetate succinate) is our second enteric coating material, and it was developed for aqueous coating. Shin-Etsu AQOAT® was approved as a pharmaceutical excipient in Japan in 1987, and then in the United States and several European countries in 2001. In an aqueous system, a suspension containing Shin-Etsu AQOAT® (fine powder), triethyl citrate as a plasticizer, talc as an anti-tacking agent, and sodium lauryl sulfate as a wetting agent is typically used.
      Shin-Etsu AQOAT® also shows excellent performance when it is used as a carrier for solid dispersions in order to enhance solubility of poorly soluble drugs.

      Series Name

      • AQOAT series

      Applications

      • Enteric film coating for solid dosage forms such as tablets and granules
      • Drug solubility enhancement (solid dispersion)
      • Taste masking
      • Sustained release pH dependent
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      For Inquiries About This Product
      • Company:
        Shin-Etsu Chemical Co., Ltd.
      • Department:
        Cellulose & Pharmaceutical Excipients Department Organic Chemicals Division
      • Phone:
        +81-3-3246-5261
      
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